The adaptability and danger of Liriomyza huidobrensis Blanchard were comprehensively analyzed in Guizhou flue-cured tobacco growing regions. The results indicated that most of the regions were favorable or optimum for habitation of Liriomyza huidobrensis Blanchard, but damage and risk to tobacco growth were very limited due to contribution from other crops. However, with the increasing commercial production of tobacco seedlings, more attention should be paid to the insect monitor and control in tobacco seedling stage.