The Fuzzy comprehensive adjust method was adopted to evaluate soil fertility level in several tobacco planting regions based on nutrient analytical data of 516 topsoil samples from 11 counties（ cities）in Guangdong Province. The results showed that the average IFI value of tobacco growing soils was 0.590,，and generally the comprehensive nutrient fertility was the third grade. Most of them belonged to the second and third grade which accounted for 64.15%. According to the types of tobacco growing soil,，the IFI value of Honghuonidi,Niugantutian, Shanitian,calcareous soil and purple soil was 0.531，0.751,，0.529,，0.739 and 0.639 respectively.