A new flue- cured tobacco variety Yuyan 4 was developed from Xujin 1(female parent) and coker176 (male parent) with a genealogy method and passed the national tobacco evaluation in March 2006.The results of multi- location trials for several years showed that with stable agronomic characteristics, Yuyan 4 grew uniformly and vigorously in field and had a growing period of 113- 110 days. It was resistant to black shank, moderately resistant to root- knot nematode and CMV. Its leaves matured well layer by layer and easy to be cured. The cured leaves were in orange color, loosely structured, oily with strong aroma and average body. The content and ratio of the major chemical components were suitable. Its average yield, price, first grade leaf proportion, output value were 2273 kg / hm2,7.01yuan / kg,21.86% and 15909.22 yuan / hm2, respectively. Yuyan 4 is superior in terms of general characteristics compared with the control variety NC89.