Principal component analysis and systemic cluster analysis were used to analyze 12 nutrient indices of 91 soil samples from Zunyi. Four principal components and general index of each flue-cured tobacco planting county were obtained. According to the cluster graph and 8 distance modulus，the soil samples of Zunyi were divided into 5 groups. The first group was Zunyi county with high nitrogen (N), high phosphorus (P), and middle potassium (K). The second group included Meitan, Yuqing, Daozhen, and Wuchuan, whose characters were middle N, middle P and middle K. The third group was Suiyang with middle N, middle P and high K. The fourth group included Tongzi, Fenggang and Zheng’an, whose characters were middle N, middle P and low K. The last group was Renhuai with low N, low P, and middle K.