SiRNA介導(dǎo)的基因沉默及其在植物抗病毒應(yīng)用中的研究進(jìn)展
SiRNA Induced Gene Silencing and Its Application in Plant Anti-virus
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摘要: 基因沉默是由雙鏈RNA介導(dǎo)的同源RNA的降解現(xiàn)象,，是一種古老的RNA監(jiān)控系統(tǒng)，協(xié)助生物體抵抗外來核酸的入侵,?；虺聊到y(tǒng)是植物抵抗病毒侵染的防衛(wèi)體系，在長期的協(xié)同進(jìn)化過程中,，由病毒編碼的抑制蛋白可以抵消基因沉默系統(tǒng)的作用,。本文對(duì)基因沉默的過程、病毒編碼的抑制子蛋白及基因沉默在植物抗病毒工程的研究進(jìn)展進(jìn)行簡(jiǎn)要綜述,。Abstract: Gene silencing is a phenomenon of homologous RNA degradation, which might have arisen as an ancient RNA surveillance system that acts as a natural defense mechanism against invasive nucleic acids. From long period evolution with plants, plant virus obtains the ability to code gene silencing suppressors against this defense system. This paper reviewed the advancement of gene silencing mechanism, silencing suppressors coded by virus, and the application of gene silencing in plant anti-virus engineering.
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